Transient Shortening of Microvilli Induced by Cycloheximide in the Duodenal Epithelium of the Chicken

INTRODUCTION that maintain the microvilli or that control the As intestinal epithelial cells migrate from the alterations during migration of the epithelial crypts of Lieberkuhn to the tip of a villus, their cells . Recent estimates of protein turnover rates in microvilli become longer and narrower and prethe rat intestine suggest, however, that microvilli suma are not static structures, but probably represent a bly increase in number per cell (1) . These steady state governed by rates of synthesis and morphological alterations are accompanied by degradation of their molecular components (4) . marked changes in the activities of the hydrolytic Inhibitors of RNA and protein synthesis have